Top Startups in San Francisco Bay Area - 2026 Startup Directory

BioAge Labs

BIOAGE targets aging to develop drugs that treat severe diseases Biotech

Last round: Series D Andreessen Horowitz, $170M Series D in 2024

Karius

Karius provides genomic insights for infectious diseases to enable clinicians to make life-saving treatment decisions. Biotech Genetics Healthcare

Last round: Series B Khosla Ventures, $165M Series B in 2020

Plate IQ

Plate IQ is leading AP automation software specifically designed for restaurants. Marketing Software Small & Medium Businesses Restaurants

Last round: Series B Y Combinator, $160M Series B in 2021

Primer

Primer is an online community where 7-14-year-olds spend their time coding video games. SaaS EdTech

Last round: Series A Founders Fund, Khosla Ventures, $15M Series A in 2022

Fountain Therapeutics

Fountain Therapeutics is discovering and developing treatments for aging-associated diseases. Biotech Healthcare Medical

Last round: Series A Khosla Ventures, $15M Series A in 2021

FidoCure

FidoCure is a social impact company. We are the first to bring precision therapies, used in humans, to dogs with cancer. Healthcare Pets

Last round: Series A Y Combinator, $15M Series A in 2020

Ironclad

Ironclad is one of the nation’s top makers of enterprise software for managing contracts Enterprise Software Legal Tech

Last round: Series E Sequoia, Y Combinator, Accel, $150M Series E in 2022, $3.2B valuation

snapdocs

Snapdocs is a mortgage technology company that helps real estate participants work together through integration and automation. Real Estate FinTech

Last round: Series D Sequoia, Founders Fund, Y Combinator, $150M Series D in 2021, $1.5B valuation

Truepill

Truepill is a B2B pharmacy fulfillment service. Healthcare Pharmaceuticals

Last round: Series D Y Combinator, $142M Series D in 2021, $1.6B valuation

Catch&Release

Catch&Release is a content licensing platform that enables brands and advertisers to license content from anywhere Image Recognition Content Artificial Intelligence

Last round: Series A Accel, $14M Series A in 2021

Naked Labs

Naked Labs is a startup focusing on 3D scanning, computer vision, and human-centered design. Healthcare Fitness 3DTech

Last round: Series A Founders Fund, $14M Series A in 2018

Zum

Zūm is a provider of safe, efficient, and reliable child transportation for school districts and busy families. Transportation Ride Sharing Child Care

Last round: Series E Sequoia, $140M Series E in 2024, $1.3B valuation

Medium

Medium is a social publishing network that connects ideas and perspectives on topics that matter. Consumer Media Blogging

Last round: Series C Andreessen Horowitz, $132M Series C in 2021

Squint

Squint makes every operator an expert Artificial Intelligence Augmented Reality Enterprise Software

Last round: Series A Sequoia, $13M Series A in 2023

WorkWhile

WorkWhile is a labor technology platform that helps workers find jobs that fit their skills, schedule, and location. Recruiting

Last round: Series A Khosla Ventures, $13M Series A in 2022

Apollo

Apollo builds open source tools that integrate GraphQL across all apps and services. Developer Tools Enterprise Software

Last round: Series D Andreessen Horowitz, $130M Series D in 2021, $1.5B valuation

AliveCor

AliveCor is a FDA-cleared mobile heart solution that helps save lives and money Healthcare Hardware Medical Devices

Last round: Series F Khosla Ventures, $128M Series F in 2022

Cresta

Cresta leverages artificial intelligence to help sales and service agents improve the quality of their customer service Artificial Intelligence Sales Enterprise Software

Last round: Series D Sequoia, Andreessen Horowitz, $125M Series D in 2024

BillionToOne

BillionToOne is a precision diagnostics company that makes molecular diagnostics. Healthcare Medical Biotech

Last round: Series C Y Combinator, $125M Series C in 2022

Density

Density builds the technical infrastructure for cities, buildings, and spaces to measure how they're used. Analytics Sensor Enterprise Software

Last round: Series D Kleiner Perkins, Founders Fund, $125M Series D in 2021, $1.0B valuation

Bolt Threads

We harness proteins found in nature to create materials with practical and revolutionary uses Hardware Biotech

Last round: Series D Founders Fund, $123M Series D in 2018

Silo

Silo is a wholesale food marketplace that enables customers to buy and sell produce, protein, dairy, and shelf-stable food quickly. Agriculture Marketplace

Last round: Series A Andreessen Horowitz, $12M Series A in 2020

Phiar Technologies

Phiar's Ultra-lightweight Spatial AI Engine enables vehicles to perceive its surroundings, and powers our first use case in AR Navigation. Autonomous Vehicles Data Science Deep Learning Artificial Intelligence

Last round: Series A Y Combinator, $12M Series A in 2021

Confident Cannabis

We provide wholesale cannabis and lab testing software to the industry SaaS E-Commerce Cannabis

Last round: Series A Y Combinator, $12M Series A in 2019

CloudTrucks

CloudTrucks offers a virtual trucking carrier application designed to reduce operating costs for truck drivers. Transportation Logistics

Last round: Series B Khosla Ventures, $115M Series B in 2021, $850M valuation

Run The World

Run The World is a digital event platform that is designed to host all types of events from cocktail parties to global conferences. Events SaaS

Last round: Series A Andreessen Horowitz, Founders Fund, $11M Series A in 2020

Wallarm

Wallarm is a new way of defending your web frontends and APIs against cyber attacks. Cybersecurity Enterprise Software

Last round: Series A Y Combinator, $11M Series A in 2018

Labelbox

Labelbox creates and manages labeled data for machine learning applications. Enterprise Software ML Infrastructure Artificial Intelligence

Last round: Series D Andreessen Horowitz, Kleiner Perkins, $110M Series D in 2022, $900M valuation

Strava

Strava is an online network where runners and cyclists can record their activities, compare performance, and compete with their community. Consumer Social Healthcare Fitness

Last round: Series F Sequoia, $110M Series F in 2020, $1.5B valuation

Inflammatix

Inflammatix develops a novel molecular diagnostics for acute infections and sepsis that work by reading the immune system. Healthcare Medical

Last round: Series D Khosla Ventures, $102M Series D in 2021

Tara Intelligence

Tara AI helps modern software teams manage and deliver across their product development lifecycle. Enterprise Software Product Development

Last round: Series A Y Combinator, $10M Series A in 2019, $40M valuation

Pave

Pave leverages real-time HR and equity integrations to help companies plan, communicate, and benchmark compensation. Human Resources Compensation Enterprise Software

Last round: Series C Andreessen Horowitz, Bessemer, Y Combinator, $100M Series C in 2022, $1.6B valuation

Tecton.AI

Tecton provides an enterprise-ready feature store to make machine learning accessible to every company. Enterprise Software ML Infrastructure Artificial Intelligence

Last round: Series C Sequoia, Andreessen Horowitz, Kleiner Perkins, $100M Series C in 2022

CaptivateIQ

Building modern sales compensation software to help businesses motivate teams. Sales Enterprise Software

Last round: Series C Sequoia, Accel, $100M Series C in 2022, $1.2B valuation

CoinTracker

CoinTracker is a portfolio and tax manager for cryptocurrency. FinTech Crypto

Last round: Series A Accel, Y Combinator, $100M Series A in 2022, $1.3B valuation

Ethos Life

Ethos Life is a modern insurance company that provides ethical life insurance. FinTech Life Insurance

Last round: Series D Sequoia, $100M Series D in 2021, $2.7B valuation

Manticore Games

Manticore Games develops hardcore multiplayer PC and console games, using the Unreal 4 engine. Gaming

Last round: Series C Benchmark, $100M Series C in 2021

Viz

Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology. Artificial Intelligence Healthcare

Last round: Series D Kleiner Perkins, $100M Series D in 2022, $1.2B valuation

Color

Color is a population health technology company that enables the delivery of advanced healthcare through clinical genetics. Healthcare Biotech

Last round: Series E Khosla Ventures, $100M Series E in 2021, $4.6B valuation

Imply

Imply delivers real-time ingestion and visualizations for event-driven and streaming data flows. Enterprise Software Analytics Data Science

Last round: Series D Khosla Ventures, Andreessen Horowitz, Bessemer, $100M Series D in 2022, $1.1B valuation

Benchling

Building Office Suite for pharma, biotech, life sciences research Healthcare Biotech

Last round: Series F Sequoia, Andreessen Horowitz, Benchmark, Y Combinator, $100M Series F in 2021, $6.1B valuation

Good Eggs

Good Eggs is an online grocer and meal kit delivery service with a mission to reinvent the food system, for good. Groceries Delivery

Last round: Series D Benchmark, $100M Series D in 2021

Voiceops

We help sales managers build more effective teams and processes. SaaS Sales Automation

Last round: Series A Founders Fund, Y Combinator, Accel, $9M Series A in 2021

Castle

Intelligent protection against user account fraud and hijacks. Cybersecurity Fraud Detection

Last round: Series A Khosla Ventures, $9M Series A in 2019

Nuna

Nuna works with government, employers, and plans to improve how people use healthcare through data. Healthcare

Last round: Series B Kleiner Perkins, $90M Series B in 2017

Turing

Turing enables businesses to hire software engineers Recruiting Freelancers Developers

Last round: Series B Founders Fund, $87M Series B in 2021, $1.1B valuation

Qventus

Qventus optimizes decisions in hospitals in real time to reduce costs, improve quality and experience. Predictive Analytics Healthcare

Last round: Series D Bessemer, Y Combinator, $85M Series D in 2025

Simplified

Simplified helps you design everything, scale your brand, and collaborate with your team like never before. SaaS Design Collaboration

Last round: Seed Khosla Ventures, $8M Seed in 2021