Startup Directory
Boston Startups
Discover startups in Boston with funding rounds, founder profiles, sector clusters, hiring signals, and connected country or market news coverage.
Research Brief
How to read this Boston startup list
This page organizes startups in Boston by funding, founder, category, hiring, and company momentum signals. The goal is to help readers move from a broad location search into specific company profiles, founder context, market categories, and funding-stage comparisons. Pages with stronger data depth remain selected for deeper public coverage; lower-volume pages stay live for readers as lightweight discovery routes until the market coverage improves.
Startup market context for Boston
Boston startup discovery is most useful when geography is connected to sector density, hiring motion, investor access, and recent funding. A city or country page should not only list companies; it should explain where founder activity is forming, which sectors are attracting capital, and which companies are building repeatable traction. This directory currently tracks 38 indexed companies for this location context.
Commonwealth Fusion
Building the path to clean, carbon-free, limitless energy Sustainability Renewable Energies
Last round: Series B Khosla Ventures, $2B Series B in 2021
ROME Therapeutics
ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome. Biotech Healthcare Pharmaceuticals
Last round: Series B Andreessen Horowitz, $50M Series B in 2021, $70M valuation
Scipher Medicine
Scipher Medicine develops a healthcare platform designed to determine which drug will work best for each patient. Healthcare Biotech
Last round: Series D Khosla Ventures, $110M Series D in 2022
Biofourmis
Biofourmis is a biotechnology company that augments personalized care and therapies using digital therapeutics. Healthcare Biotech
Last round: Series C Sequoia, $100M Series C in 2020, $700M valuation
Silk
Silks optimizes the cloud, allowing organizations to get 10x the performance while spending 30% less SaaS Enterprise Software
Last round: Series B Sequoia, $55M Series B in 2021
Zus Health
Zus empowers an entirely new wave of healthcare builders to create technologies and services without the usual blockers Healthcare Medical Software
Last round: Series A Andreessen Horowitz, $40M Series A in 2023
DH
Devoted Health
Devoted Health is a healthcare company serving seniors and giving them a health care plan with personal guides and world-class technology. Healthcare Elder Care
Last round: Series D Andreessen Horowitz, $362M Series D in 2021, $1.1B valuation
Starburst Data
Starburst Data is a data access and analytics company developing an SQL query engine. Software Analytics Data Science
Last round: Series D Andreessen Horowitz, $250M Series D in 2022, $3.4B valuation
Asimov
Asimov builds tools to program living cells. Biotech
Last round: Series B Andreessen Horowitz, $175M Series B in 2023
eGenesis
eGenesis is a life sciences company focused on development and commercialization of engineered organisms for the benefit of human health. Biotech
Last round: Series C Khosla Ventures, $125M Series C in 2021, $99M valuation
Digital.ai
Leading provider of software delivery automation for the enterprise. Enterprise Software Developer Tools
Last round: Series B Accel, $122M Series B in 2018
Dyno Therapeutics
Dyno Therapeutics uses artificial intelligence for gene therapy. Healthcare Biotech Artificial Intelligence
Last round: Series A Andreessen Horowitz, $100M Series A in 2021
CAMP4 Therapeutics
BioTech. Solving how genes are controlled to drive the efficient development of treatments. Biotech
Last round: Series B Andreessen Horowitz, $100M Series B in 2022
Devo
Devo is a cybersecurity company that provides cloud-native logging and security analytics for organizations. Cybersecurity Enterprise Software
Last round: Series F Bessemer, $100M Series F in 2022, $2.0B valuation
Fractyl Labs
Developing an Innovative Endoscopic Outpatient Procedure to Improve Glycemic Control for Type 2 Diabetes Healthcare Medical Devices
Last round: Series F Bessemer, $100M Series F in 2021
E
Emulate
Emulate is focused on commercializing Organs-on-Chips. Healthcare Biotech
Last round: Series E Founders Fund, $82M Series E in 2021
Cellino
Cellino Biotech develops intracellular delivery lasers and nanotechnology for gene editing applications. Biotech Nanotechnology
Last round: Series A Khosla Ventures, $80M Series A in 2022
Plastiq
Plastiq offers a bill pay service for businesses to better manage their cash flow. FinTech Payments
Last round: Series D Khosla Ventures, Kleiner Perkins, $75M Series D in 2020, $700M valuation
10% Happier
Health and wellness platform that offers a simple approach to meditation. EdTech Healthcare Apps
Last round: Series A Khosla Ventures, $5M Series A in 2018
Claim
Discover your new favorite things, earn cash back, and share the benefits with friends Consumer Social E-Commerce
Last round: Seed Sequoia, $4M Seed in 2023
DUST Identity
We link physical objects to their digital records securely. Cybersecurity Nanotechnology
Last round: Series B Kleiner Perkins, $40M Series B in 2023
Neural Magic
Machine learning without limits Machine Learning Artificial Intelligence Software
Last round: Series A Andreessen Horowitz, $30M Series A in 2021
Elemental Machines
Smart lab platform delivers powerful, data-driven insights that improve R&D, laboratory operations, and manufacturing outcomes. Biotech SaaS
Last round: Series A Founders Fund, $2M Series A in 2020
Ori
Ori is a smart space company that designs multi-functional, robotic-powered interior solutions. Robotics Architecture Hardware
Last round: Series B Khosla Ventures, $20M Series B in 2022
Agrivida
Agrivida creates renewable, biomass-based alternative fuels and raw materials. Sustainability Biotech
Last round: Series E Kleiner Perkins, $20M Series E in 2016
Centaur Labs
Labeling medical images at scale Artificial Intelligence Data Science Machine Learning Healthcare
Last round: Series A Y Combinator, $15M Series A in 2021
Connie Health
Connie Health empowers older Americans to make confident, worry-free healthcare decisions. Healthcare Medical
Last round: Series A Khosla Ventures, $13M Series A in 2021
Raptor Maps
Raptor Maps optimizes produce farming by using tractor-mounted sensors and drones Drones Agriculture Hardware
Last round: Series A Y Combinator, $5M Series A in 2020
Alpha Vantage
APIs for financial market data FinTech Crypto API
Last round: Seed Y Combinator, $2M Seed in 2018
HigherMe
HigherMe uses data and video to help retail and service employers find, screen, and hire better employees faster. SaaS Recruiting Video
Last round: Growth Y Combinator, Raised $2M in 2016
Clear Ballot Group
Clear Ballot develops modern solutions for voting, absentee, and audit systems. GovTech Software
Last round: Growth Bessemer, Raised $18M in 2017
Circle
Circle is a global internet finance company, built on blockchain technology and powered by crypto assets. FinTech Crypto Banking
Last round: IPO Accel, Post-IPO, $9.0B valuation
Toast
The all-in-one POS and restaurant management platform. Software Point of Sale Restaurants
Last round: IPO Bessemer, Post-IPO, $10.0B valuation
Kymera Therapeutics
Kymera Therapeutics is pioneering a transformative approach to treating previously untreatable diseases. Healthcare Biotech
Last round: IPO Bessemer, Post-IPO, $2.0B valuation
VS
Vicarious Surgical
Vicarious Surgical improves the lives of patients and surgeons by giving access to high quality care through the use of surgical robotics. Healthcare Medical Devices Hardware
Last round: IPO Khosla Ventures, Post-IPO, $700M valuation
Berkshire Grey
Berkshire Grey develops a materials handling system to automate omnichannel fulfillment. Hardware Logistics Robotics
Last round: IPO Khosla Ventures, Post-IPO, $700M valuation
TransMedics
Transmedics is a medical device company for transplant devices. Healthcare Medical Medical Devices
Last round: IPO Kleiner Perkins, Post-IPO, $400M valuation
Desktop Metal
Changing the way the world makes metal parts Hardware 3D Printing
Last round: IPO Kleiner Perkins, Post-IPO, $120M valuation
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FAQ
Questions about Boston startups
What is this Boston startup page?
It is a 100Xfounder directory page for startups in Boston, combining company profiles, founder context, funding signals, hiring indicators, and internal links into related market pages. 38 companies are currently included in this view.
How are startups in Boston selected?
The page uses structured 100Xfounder company and founder data, then groups profiles by location. Ordering favors stronger funding, verified company context, founder detail, hiring signals, and useful internal research paths.
How complete is this market page?
This page currently has enough company depth for a full public market brief and inclusion in discovery feeds.
Where should I go next after this Boston list?
Use related founder profiles, company pages, funding-round pages, country hubs, startup jobs, salary-equity pages, and newsroom coverage to understand the broader market context around these companies.
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