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Startup Directory

Boston Startups

Discover startups in Boston with funding rounds, founder profiles, sector clusters, hiring signals, and connected country or market news coverage.

38 companies indexedFunding-first ordering

Research Brief

How to read this Boston startup list

This page organizes startups in Boston by funding, founder, category, hiring, and company momentum signals. The goal is to help readers move from a broad location search into specific company profiles, founder context, market categories, and funding-stage comparisons. Pages with stronger data depth remain selected for deeper public coverage; lower-volume pages stay live for readers as lightweight discovery routes until the market coverage improves.

Startup market context for Boston

Boston startup discovery is most useful when geography is connected to sector density, hiring motion, investor access, and recent funding. A city or country page should not only list companies; it should explain where founder activity is forming, which sectors are attracting capital, and which companies are building repeatable traction. This directory currently tracks 38 indexed companies for this location context.

Commonwealth Fusion logoCF
Commonwealth Fusion Team

Commonwealth Fusion

Building the path to clean, carbon-free, limitless energy Sustainability Renewable Energies

Last round: Series B Khosla Ventures, $2B Series B in 2021

$2.00BBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
ROME Therapeutics logoRT
ROME Therapeutics Team

ROME Therapeutics

ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome. Biotech Healthcare Pharmaceuticals

Last round: Series B Andreessen Horowitz, $50M Series B in 2021, $70M valuation

$50.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Scipher Medicine logoSM
Scipher Medicine Team

Scipher Medicine

Scipher Medicine develops a healthcare platform designed to determine which drug will work best for each patient. Healthcare Biotech

Last round: Series D Khosla Ventures, $110M Series D in 2022

$110.00MBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
Biofourmis logoB
Biofourmis Team

Biofourmis

Biofourmis is a biotechnology company that augments personalized care and therapies using digital therapeutics. Healthcare Biotech

Last round: Series C Sequoia, $100M Series C in 2020, $700M valuation

$100.00MBoston, Massachusetts, USA201-500 employees EmployeesHiring: Open Roles
Silk logoS
Silk Team
Silk TeamVerified

Silk

Silks optimizes the cloud, allowing organizations to get 10x the performance while spending 30% less SaaS Enterprise Software

Last round: Series B Sequoia, $55M Series B in 2021

$55.00MBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
Zus Health logoZH
Zus Health Team

Zus Health

Zus empowers an entirely new wave of healthcare builders to create technologies and services without the usual blockers Healthcare Medical Software

Last round: Series A Andreessen Horowitz, $40M Series A in 2023

$40.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
Devoted Health logoDH
Devoted Health Team

Devoted Health

Devoted Health is a healthcare company serving seniors and giving them a health care plan with personal guides and world-class technology. Healthcare Elder Care

Last round: Series D Andreessen Horowitz, $362M Series D in 2021, $1.1B valuation

$362.00MBoston, Massachusetts, USA501-1000 employees EmployeesHiring: Open Roles
Starburst Data logoSD
Starburst Data Team

Starburst Data

Starburst Data is a data access and analytics company developing an SQL query engine. Software Analytics Data Science

Last round: Series D Andreessen Horowitz, $250M Series D in 2022, $3.4B valuation

$250.00MBoston, Massachusetts, USA201-500 employees EmployeesHiring: Open Roles
Asimov logoA
Asimov Team
Asimov TeamVerified

Asimov

Asimov builds tools to program living cells. Biotech

Last round: Series B Andreessen Horowitz, $175M Series B in 2023

$175.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
eGenesis logoE
eGenesis Team

eGenesis

eGenesis is a life sciences company focused on development and commercialization of engineered organisms for the benefit of human health. Biotech

Last round: Series C Khosla Ventures, $125M Series C in 2021, $99M valuation

$125.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
Digital.ai logoD
Digital.ai Team

Digital.ai

Leading provider of software delivery automation for the enterprise. Enterprise Software Developer Tools

Last round: Series B Accel, $122M Series B in 2018

$122.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Dyno Therapeutics logoDT
Dyno Therapeutics Team

Dyno Therapeutics

Dyno Therapeutics uses artificial intelligence for gene therapy. Healthcare Biotech Artificial Intelligence

Last round: Series A Andreessen Horowitz, $100M Series A in 2021

$100.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
CAMP4 Therapeutics logoCT
CAMP4 Therapeutics Team

CAMP4 Therapeutics

BioTech. Solving how genes are controlled to drive the efficient development of treatments. Biotech

Last round: Series B Andreessen Horowitz, $100M Series B in 2022

$100.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
Devo logoD
Devo Team
Devo TeamVerified

Devo

Devo is a cybersecurity company that provides cloud-native logging and security analytics for organizations. Cybersecurity Enterprise Software

Last round: Series F Bessemer, $100M Series F in 2022, $2.0B valuation

$100.00MBoston, Massachusetts, USA501-1000 employees EmployeesHiring: Open Roles
Fractyl Labs logoFL
Fractyl Labs Team

Fractyl Labs

Developing an Innovative Endoscopic Outpatient Procedure to Improve Glycemic Control for Type 2 Diabetes Healthcare Medical Devices

Last round: Series F Bessemer, $100M Series F in 2021

$100.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
Emulate logoE
Emulate Team
Emulate TeamVerified

Emulate

Emulate is focused on commercializing Organs-on-Chips. Healthcare Biotech

Last round: Series E Founders Fund, $82M Series E in 2021

$82.00MBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
Cellino logoC
Cellino Team
Cellino TeamVerified

Cellino

Cellino Biotech develops intracellular delivery lasers and nanotechnology for gene editing applications. Biotech Nanotechnology

Last round: Series A Khosla Ventures, $80M Series A in 2022

$80.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Plastiq logoP
Plastiq Team
Plastiq TeamVerified

Plastiq

Plastiq offers a bill pay service for businesses to better manage their cash flow. FinTech Payments

Last round: Series D Khosla Ventures, Kleiner Perkins, $75M Series D in 2020, $700M valuation

$75.00MBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
10% Happier logo1H
10% Happier Team

10% Happier

Health and wellness platform that offers a simple approach to meditation. EdTech Healthcare Apps

Last round: Series A Khosla Ventures, $5M Series A in 2018

$5.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
Claim logoC
Claim Team
Claim TeamVerified

Claim

Discover your new favorite things, earn cash back, and share the benefits with friends Consumer Social E-Commerce

Last round: Seed Sequoia, $4M Seed in 2023

$4.00MBoston, Massachusetts, USA1-10 employees EmployeesHiring: Open Roles
DUST Identity logoDI
DUST Identity Team

DUST Identity

We link physical objects to their digital records securely. Cybersecurity Nanotechnology

Last round: Series B Kleiner Perkins, $40M Series B in 2023

$40.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Neural Magic logoNM
Neural Magic Team

Neural Magic

Machine learning without limits Machine Learning Artificial Intelligence Software

Last round: Series A Andreessen Horowitz, $30M Series A in 2021

$30.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Elemental Machines logoEM
Elemental Machines Team

Elemental Machines

Smart lab platform delivers powerful, data-driven insights that improve R&D, laboratory operations, and manufacturing outcomes. Biotech SaaS

Last round: Series A Founders Fund, $2M Series A in 2020

$2.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Ori logoO
Ori Team
Ori TeamVerified

Ori

Ori is a smart space company that designs multi-functional, robotic-powered interior solutions. Robotics Architecture Hardware

Last round: Series B Khosla Ventures, $20M Series B in 2022

$20.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Agrivida logoA
Agrivida Team

Agrivida

Agrivida creates renewable, biomass-based alternative fuels and raw materials. Sustainability Biotech

Last round: Series E Kleiner Perkins, $20M Series E in 2016

$20.00MBoston, Massachusetts, USA11-50 employees Employees
Centaur Labs logoCL
Centaur Labs Team

Centaur Labs

Labeling medical images at scale Artificial Intelligence Data Science Machine Learning Healthcare

Last round: Series A Y Combinator, $15M Series A in 2021

$15.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Connie Health logoCH
Connie Health Team

Connie Health

Connie Health empowers older Americans to make confident, worry-free healthcare decisions. Healthcare Medical

Last round: Series A Khosla Ventures, $13M Series A in 2021

$13.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Raptor Maps logoRM
Raptor Maps Team

Raptor Maps

Raptor Maps optimizes produce farming by using tractor-mounted sensors and drones Drones Agriculture Hardware

Last round: Series A Y Combinator, $5M Series A in 2020

$5.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
Alpha Vantage logoAV
Alpha Vantage Team

Alpha Vantage

APIs for financial market data FinTech Crypto API

Last round: Seed Y Combinator, $2M Seed in 2018

$2.00MBoston, Massachusetts, USA1-10 employees Employees
HigherMe logoH
HigherMe Team

HigherMe

HigherMe uses data and video to help retail and service employers find, screen, and hire better employees faster. SaaS Recruiting Video

Last round: Growth Y Combinator, Raised $2M in 2016

$2.00MBoston, Massachusetts, USA11-50 employees EmployeesHiring: Open Roles
Clear Ballot Group logoCB
Clear Ballot Group Team

Clear Ballot Group

Clear Ballot develops modern solutions for voting, absentee, and audit systems. GovTech Software

Last round: Growth Bessemer, Raised $18M in 2017

$18.00MBoston, Massachusetts, USA51-100 employees EmployeesHiring: Open Roles
Circle logoC
Circle Team
Circle TeamVerified

Circle

Circle is a global internet finance company, built on blockchain technology and powered by crypto assets. FinTech Crypto Banking

Last round: IPO Accel, Post-IPO, $9.0B valuation

$9.00BBoston, Massachusetts, USA201-500 employees EmployeesHiring: Open Roles
Toast logoT
Toast Team
Toast TeamVerified

Toast

The all-in-one POS and restaurant management platform. Software Point of Sale Restaurants

Last round: IPO Bessemer, Post-IPO, $10.0B valuation

$10.00BBoston, Massachusetts, USA1001-5000 employees EmployeesHiring: Open Roles
Kymera Therapeutics logoKT
Kymera Therapeutics Team

Kymera Therapeutics

Kymera Therapeutics is pioneering a transformative approach to treating previously untreatable diseases. Healthcare Biotech

Last round: IPO Bessemer, Post-IPO, $2.0B valuation

$2.00BBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
Vicarious Surgical logoVS
Vicarious Surgical Team

Vicarious Surgical

Vicarious Surgical improves the lives of patients and surgeons by giving access to high quality care through the use of surgical robotics. Healthcare Medical Devices Hardware

Last round: IPO Khosla Ventures, Post-IPO, $700M valuation

$700.00MBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
Berkshire Grey logoBG
Berkshire Grey Team

Berkshire Grey

Berkshire Grey develops a materials handling system to automate omnichannel fulfillment. Hardware Logistics Robotics

Last round: IPO Khosla Ventures, Post-IPO, $700M valuation

$700.00MBoston, Massachusetts, USA201-500 employees EmployeesHiring: Open Roles
TransMedics logoT
TransMedics Team

TransMedics

Transmedics is a medical device company for transplant devices. Healthcare Medical Medical Devices

Last round: IPO Kleiner Perkins, Post-IPO, $400M valuation

$400.00MBoston, Massachusetts, USA101-200 employees EmployeesHiring: Open Roles
Desktop Metal logoDM
Desktop Metal Team

Desktop Metal

Changing the way the world makes metal parts Hardware 3D Printing

Last round: IPO Kleiner Perkins, Post-IPO, $120M valuation

$120.00MBoston, Massachusetts, USA201-500 employees EmployeesHiring: Open Roles
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FAQ

Questions about Boston startups

What is this Boston startup page?

It is a 100Xfounder directory page for startups in Boston, combining company profiles, founder context, funding signals, hiring indicators, and internal links into related market pages. 38 companies are currently included in this view.

How are startups in Boston selected?

The page uses structured 100Xfounder company and founder data, then groups profiles by location. Ordering favors stronger funding, verified company context, founder detail, hiring signals, and useful internal research paths.

How complete is this market page?

This page currently has enough company depth for a full public market brief and inclusion in discovery feeds.

Where should I go next after this Boston list?

Use related founder profiles, company pages, funding-round pages, country hubs, startup jobs, salary-equity pages, and newsroom coverage to understand the broader market context around these companies.

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