Top Startups in San Francisco Bay Area - 2026 Startup Directory

Safe Superintelligence

World's first straight-shot safe superintelligence lab Artificial Intelligence

Last round: Series A Sequoia, Andreessen Horowitz, $1B Series A in 2024

ClickHouse

Open-source database system for real-time analytical reporting SaaS Analytics Enterprise Software

Last round: Series C Benchmark, $350M Series C in 2025, $6.0B valuation

Harvey

AI provider for legal workers Artificial Intelligence Legal

Last round: Series E Sequoia, Kleiner Perkins, $300M Series E in 2025, $5.0B valuation

Ambience Healthcare

AI operating system used for documentation, coding, and clinical workflows Artificial Intelligence Healthcare

Last round: Series C Andreessen Horowitz, $243M Series C in 2025

World Labs

Develops AI models with spatial intelligence for 3D world perception and interaction Artificial Intelligence

Last round: Series A Andreessen Horowitz, $230M Series A in 2024, $1.0B valuation

Varda

Varda is a space manufacturing startup which focuses on creating products in space for terrestrial applications. Manufacturing Space

Last round: Series C Khosla Ventures, Founders Fund, $187M Series C in 2025

Codeium

Modern coding superpower Artificial Intelligence SaaS

Last round: Series C Kleiner Perkins, $150M Series C in 2024, $1.2B valuation

NewLimit

Developing epigenetic therapies to extend human healthspan by reprogramming aging cells Biotech Healthcare

Last round: Series B Founders Fund, $130M Series B in 2025

Together

Fastest cloud platform for building and running gen AI Artificial Intelligence

Last round: Series A Kleiner Perkins, $106M Series A in 2024, $1.2B valuation

mmhmm

mmhmm is a virtual camera application used to create virtual rooms, backdrops, and presentations during video calls. Video Chat SaaS

Last round: Series B Sequoia, $100M Series B in 2021

xAI

Accelerate human scientific discovery Artificial Intelligence

Last round: Series B Sequoia, Andreessen Horowitz, $6B Series B in 2024, $24.0B valuation

Anthropic

AI safety-first model company building enterprise-ready Claude assistants and APIs.

Last round: Strategic $4B

Flexport

Flexport is a licensed freight forwarder that uses people and software to manage the complexity of international trade. Logistics E-Commerce Freight Supply Chain

Last round: Series E Andreessen Horowitz, Founders Fund, Y Combinator, $935M Series E in 2022, $8.0B valuation

Stytch

Building passwordless authentication to start, with an eye towards making the passport of the internet Developer APIs SaaS Cybersecurity

Last round: Series B Benchmark, $90M Series B in 2021, $1.0B valuation

Airtable

Airtable offers an easy-to-use online platform for creating and sharing relational databases. SaaS Productivity Software Collaboration Databases

Last round: Series F Benchmark, $735M Series F in 2021, $11.7B valuation

Ambience

Leading AI operating system for healthcare organizations Artificial Intelligence Healthcare

Last round: Series B Kleiner Perkins, $70M Series B in 2024

Reddit

Reddit is an online platform that enables users to submit links, create content, and have discussions about the topics of their interest. Consumer Social Media Communities

Last round: Series F Sequoia, Andreessen Horowitz, $700M Series F in 2021, $10.0B valuation

Houzz

Houzz is an online platform for home remodeling, architecture, interior design, decorating, landscaping Home Design

Last round: Series E Sequoia, $614M Series E in 2021, $4.0B valuation

HeyGen

Next-gen generative AI video platform with customizable AI avatars, right from your browser Artificial Intelligence

Last round: Series B Benchmark, $60M Series B in 2024

Secureframe

Builds security and compliance software SaaS Cybersecurity

Last round: Series B Kleiner Perkins, $56M Series B in 2022

Patch

Powering climate action by making the purchase of carbon credits and neutralizing emissions as easy as clicking a button Sustainability Renewable Energies Enterprise Software

Last round: Series B Andreessen Horowitz, $55M Series B in 2022

Ema

Universal AI employee that boosts productivity across every role Artificial Intelligence Enterprise Software

Last round: Series A Accel, $50M Series A in 2024

DevRev

DevRev is a platform for managing developer-customer relationships that allow developers to build, support, and grow their businesses. Development Platforms Software

Last round: Seed Khosla Ventures, $50M Seed in 2021

Perplexity

AI-powered answer and research engine focused on fast, sourced responses.

Last round: Series C $500M

Nooks

AI dialing and prospecting platform, trusted by thousands of SDRs & AEs to cut out the busywork Artificial Intelligence Sales

Last round: Series B Kleiner Perkins, $43M Series B in 2024

Plaid

Plaid is focused on democratizing financial services through technology. FinTech API

Last round: Series D Andreessen Horowitz, $425M Series D in 2020, $13.4B valuation

Vivodyne

Accelerates drug discovery using lab-grown human tissues, robotics, and AI to generate accurate preclinical test data Artificial Intelligence Biotech Healthcare

Last round: Series A Khosla Ventures, $40M Series A in 2025

insitro

Insitro is a drug discovery and development startup that utilizes machine learning and biology to transform drug discovery. Biotech Healthcare

Last round: Series C Andreessen Horowitz, $400M Series C in 2021

Miro

Online whiteboard for remote team collaboration. Visualize, discuss and share. SaaS Design Collaboration Productivity Software Enterprise Software

Last round: Series C Accel, $400M Series C in 2022, $17.5B valuation

Pika

Idea-to-video platform that brings your creativity to motion Artificial Intelligence Consumer

Last round: Series A Lightspeed, $35M Series A in 2023, $200M valuation

Anchorage

Anchorage is a digital asset platform offering custody, trading, and financing services, as well as staking and governance. FinTech Crypto

Last round: Series D Khosla Ventures, Andreessen Horowitz, $350M Series D in 2021, $3.0B valuation

Algolia

Algolia is the Search-as-a-Service platform that enables companies to deliver fast and relevant results. Search Enterprise Software Developer APIs SaaS

Last round: Series D Accel, $334M Series D in 2021, $2.2B valuation

Solana

Solana builds and develops crypto apps for decentralized apps and marketplaces. Crypto FinTech Blockchain

Last round: Series A Andreessen Horowitz, $314M Series A in 2021

Vesta

Builds modern mortgage infrastructure stack SaaS Mortgage

Last round: Series A Andreessen Horowitz, $30M Series A in 2022

Branch

Drive seamless mobile experiences through linking infrastructure powering thousands of top brands. SaaS Mobile App Marketing

Last round: Series F Founders Fund, $300M Series F in 2022, $4.0B valuation

Forter

Decision as a Service Fraud Prevention for Online Retailers Cybersecurity Retail

Last round: Series F Sequoia, Bessemer, $300M Series F in 2021, $3.0B valuation

Niantic

Niantic builds augmented reality platform for current and future generations of AR hardware. Gaming AR/VR

Last round: Series D Founders Fund, $300M Series D in 2021, $9.0B valuation

Notion

Notion is the all-in-one workspace for your notes, tasks, wikis, and databases SaaS Enterprise Software Collaboration

Last round: Series C Sequoia, $275M Series C in 2021, $10.0B valuation

Pony.ai

Pony.ai is a developer of AI-based robot designed for autonomous driving. Robotics Artificial Intelligence Autonomous Vehicles

Last round: Series C Sequoia, $267M Series C in 2020, $8.5B valuation

Carbon

Carbon is reinventing how polymer products are designed, engineered, manufactured, and delivered, towards a digital and sustainable future. 3DTech Manufacturing

Last round: Series E Sequoia, $260M Series E in 2019, $2.5B valuation

Fireworks AI

Fireworks partners with the world's leading generative AI researchers to serve the best models, at the fastest speeds Artificial Intelligence

Last round: Series A Benchmark, $25M Series A in 2024

Flutterwave

Flutterwave is the easiest way to pay and get paid across Africa. FinTech Payments Software

Last round: Series D Y Combinator, $250M Series D in 2022, $3.0B valuation

Gong.io

Gong.io is a revenue intelligence platform that delivers insights at scale. SaaS Sales Enterprise Software

Last round: Series E Sequoia, $250M Series E in 2021, $7.2B valuation

Checkr

Checkr seeks to automate the process of professional background checks. Legal Compliance Enterprise Software SaaS

Last round: Series E Y Combinator, Accel, $250M Series E in 2021, $4.6B valuation

Intercom

Helping businesses build customer relationships via personalized, messenger-based experiences. SaaS Messaging Customer Service Sales

Last round: Series D Kleiner Perkins, Bessemer, $241M Series D in 2018, $1.2B valuation

Workboard

Workboard provides an enterprise results management platform designed to automate business reviews. Enterprise Software SaaS

Last round: Series C Andreessen Horowitz, $230M Series C in 2021, $800M valuation

Clari

Clari is a company that provides end-to-end sales analytics and a forecasting platform. Enterprise Software Analytics Sales Tools

Last round: Series F Sequoia, $225M Series F in 2022, $2.6B valuation

SendBird

Sendbird developed a messaging-as-a-service API that provides chat, voice, and video messaging Messaging Chat API SaaS Enterprise Software

Last round: Series C Y Combinator, $221M Series C in 2021, $1.0B valuation

Tempo

Tempo is a home fitness platform, combining equipment, training, and social motivation with 3D sensors and artificial intelligence. Healthcare Fitness Artificial Intelligence Hardware

Last round: Series C Khosla Ventures, Founders Fund, Y Combinator, $220M Series C in 2021, $750M valuation

Allium

Allium makes blockchain data accurate, simple and fast Artificial Intelligence Crypto

Last round: Series A Kleiner Perkins, $21M Series A in 2024